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Ceramide NP

Ceramide NP

What is Ceramide NP?

Ceramide NP, also known as Ceramide 3, is a synthetic version of a natural lipid molecule found in the skin. It helps reinforce the skin barrier, improving hydration and protecting against external stressors in skincare products.

How does this ingredient work in skincare?

Ceramide NP functions in skincare by restoring and reinforcing the lipid barrier of the stratum corneum, the outermost layer of the skin. This enhances the skin's ability to retain moisture and nutrients while preventing the penetration of harmful substances, thereby improving hydration, protecting against environmental stressors, and promoting overall skin health. Additionally, ceramide NP can modulate inflammatory responses and regulate cell proliferation, contributing to the maintenance of skin homeostasis and barrier function.

How does this ingredient compare to others?

Ceramide NP is one of several types of ceramides commonly used in skincare formulations, each with its unique properties and benefits. When compared to other ceramides, such as Ceramide AP, Ceramide EOP, or Ceramide NG, Ceramide NP (Ceramide 3) has a similar function in reinforcing the skin barrier and improving hydration. 


However, differences in molecular structure and composition may result in variations in efficacy and skin compatibility among individuals. Additionally, the concentration and formulation of ceramide NP in skincare products can influence its performance and compatibility with different skin types and concerns.

Potential benefits of this ingredient for the skin

Ceramide NP offers several potential benefits for the skin:

  • Enhanced Moisture Retention: Ceramide NP helps to restore and reinforce the skin's natural lipid barrier, which can improve the skin's ability to retain moisture. This can lead to better hydration levels, resulting in softer, smoother skin.
  • Improved Skin Barrier Function: By strengthening the lipid barrier, ceramide NP helps to protect the skin from external aggressors such as pollutants, UV radiation, and irritants. This can reduce the risk of moisture loss, sensitivity, and inflammation, promoting healthier, more resilient skin.
  • Support for Barrier Repair: Ceramide NP is particularly beneficial for individuals with compromised skin barriers, such as those with dry skin, eczema, or aging skin. It aids in the repair of the skin barrier, helping to restore its integrity and functionality over time.
  • Reduced Trans-Epidermal Water Loss (TEWL): Ceramide NP can help to decrease the rate of trans-epidermal water loss, which is beneficial for maintaining optimal hydration levels in the skin. This can prevent dryness, roughness, and discomfort associated with moisture loss.
  • Potential Anti-inflammatory Effects: Some research suggests that ceramide NP may have anti-inflammatory properties, which can help to soothe and calm irritated or inflamed skin. This can be particularly beneficial for individuals with sensitive or reactive skin conditions.

Products we use this ingredient in

Purslane Prebiotic Moisturizer, Cactus Ceramide Fortifying Milk

References

  • Lim, Sung Ha et al. “A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid.” Skin pharmacology and physiology vol. 35,2 (2022): 112-123. doi:10.1159/000518517
  • Danby, Simon G et al. “The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.” Skin pharmacology and physiology vol. 29,3 (2016): 135-47. doi:10.1159/000445955
  • Choi, Hyun Kyung et al. “Ceramide NPs derived from natural oils of Korean traditional plants enhance skin barrier functions and stimulate expressions of genes for epidermal homeostasis.” Journal of cosmetic dermatology vol. 21,10 (2022): 4931-4941. doi:10.1111/jocd.14905